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Biomedical intelligence infrastructure

Turn Biomedical Documents Into Intelligence.

BioMedora transforms complex biomedical and clinical documents into structured evidence, longitudinal patient timelines, knowledge graphs, searchable intelligence, and evidence-grounded AI insights — through one privacy-first, API-first platform.

  • Healthcare
  • Pharma
  • Biotech
  • Clinical Research
  • Life Sciences

clinical-note.txt · de-identified preview

From document to decision

One document becomes five assets

A single clinical note enters once. It leaves as structured entities, a qualified longitudinal record, a knowledge-graph neighborhood, searchable evidence, and an AI-ready grounding pack.

  1. 1

    Structured evidence

    Entities with assertion status, temporality, codes, and character-level provenance.

  2. 2

    Longitudinal record

    Cited chronological timeline — negated and family history correctly excluded.

  3. 3

    Knowledge graph

    Provenance-carrying relationships: interactions, contradictions, missing follow-ups.

  4. 4

    Searchable intelligence

    Hybrid BM25 + concept + graph retrieval over section-aware chunks.

  5. 5

    Evidence-grounded AI

    Answers whose every claim verifies against retrieved source passages.

The BioMedora wordmark
Data → Context → Knowledge → Evidence → Intelligence.
BioMedora connects all five.

The full transformation chain — explore it stage by stage below.

Jump to pipeline

Why BioMedora

The layer that connects capabilities traditionally delivered by separate tools

Generic LLMs answer. NLP libraries extract fields. Search platforms retrieve. Graph platforms store. BioMedora brings the entire chain together — with evidence traceability end to end.

  • 01

    Understands clinical context

    Not just entity extraction. Every fact carries assertion (documented, negated, family history, hypothetical, planned), temporality, coreference resolution, and relationships — because “no evidence of pneumonia” is not pneumonia.

    NegationAssertionTemporalityCoreferenceRelations
  • 02

    Builds longitudinal intelligence

    Documents become events; events become a cited chronological timeline per patient. Temporal event splitting separates “diagnosed 2014” from “recurrence 2025” as two distinct clinical moments.

    Documents → Events → Timeline
  • 03

    Connects the knowledge

    Entities link to biomedical concepts across SNOMED CT, RxNorm, LOINC, ICD, HPO, MedDRA and more, then join a knowledge graph whose every edge carries provenance back to the exact source sentence.

    Entities → Concepts → Graph
  • 04

    Grounds AI in evidence

    Every AI claim must verify against retrieved evidence with numeric fidelity checks. Unsupported statements are dropped with an uncertainty note — never silently presented as fact.

    Question → Evidence → Reasoning → Answer
  • 05

    Built API-first

    141 documented endpoints, typed Python SDKs, idempotency keys, cursor pagination, signed webhooks, and streaming chat. One platform, many integrations — from EHR to research pipelines.

    One platformMany integrations
  • 06

    Privacy by design

    De-identification sits inside the pipeline itself: consistent pseudonyms, patient-consistent date shifting, and an independent residual PHI scan that fails closed — blocked documents never proceed on a warning.

    ControlIsolationDe-identificationAuditability

Clinical NLP

Deterministic first.
Generative only where it earns trust.

BioMedora does not depend on an LLM to understand what a clinical document says. A deterministic engine establishes facts; AI reasons over them under contract-enforced guardrails.

Deterministic NLP

medspaCy TargetMatcher & ConText, lexicon fallback. Same input, same facts — every time.

What the document says

Terminology linking

SNOMED CT, RxNorm, LOINC, ICD-10-CM, MedDRA, HPO, HGVS, ATC, UCUM — UMLS-license-free by default.

Make it computable

LLM reasoning

Local open models by default; premium models opt-in. Claims validated against evidence before delivery.

Reason over evidence

Deterministic NLP + terminology linking + governed LLM reasoning = precision, repeatability, traceability, low latency, cost efficiency.

Intelligence pipeline

Twelve stages. One click each.

Explore what happens at every stage of the pipeline — what it does, why it matters, and which API endpoint drives it.

Clinical NLP

What it does
A deterministic engine — medspaCy TargetMatcher + ConText with an in-house lexicon fallback — extracts medications, conditions, labs, procedures, genes and more, with dosages, routes, reference flags, and HGVS variants.
Why it matters
Repeatability you can audit. The same document always yields the same facts — no sampling temperature involved in establishing what a document says.
Example input
Started metformin 500 mg BID.
Creatinine 1.4 mg/dL (high)
Example output
{ "text": "metformin", "type": "Medication",
  "attributes": {"dose":"500 mg","frequency":"BID"} }

Exposed via the API playground — try it live.

Patient timeline

Twenty charts become one screen

Events compile into a cited chronological record grouped by year — filterable, inspectable, and accessible. Select any event to see exactly which sentence it came from.

Filter
  1. 2019

  2. 2020

  3. 2021

  4. 2022

  5. 2023

  6. 2024

Accessible event list (screen-reader alternative)
  • Diagnosis: Type 2 diabetes diagnosed. HbA1c 8.1% at presentation; lifestyle modification advised.
  • Medication: Metformin started. Metformin 500 mg PO BID; tolerated without GI upset at follow-up.
  • Lab: Creatinine elevated. Creatinine 1.6 mg/dL (reference 0.6–1.2); repeat recommended in 90 days.
  • Procedure: Screening colonoscopy. No polyps; next screening interval 10 years.
  • Imaging: Chest X-ray finding. Mild cardiomegaly noted; comparison with prior unremarkable study.
  • Follow-up: Endocrinology follow-up. HbA1c improved to 6.7%; metformin continued; annual diabetic eye exam scheduled.

Knowledge graph

Relationships carry provenance

Every node and edge traces back to its source sentence. Click nodes to inspect concepts, dates, confidence, citations — including detected interaction risks surfaced from the knowledge base.

HAS_CONDITIONTAKES_MEDICATIONindicatesHAS_RESULTHAS_FINDINGINTERACTION_RISKPatientDEM-001Type 2 Diabetesdx 2019 · activeMetformin500 mg BID · activeCreatinine 1.6HIGH · flaggedIbuprofenPRN · activeCardiomegalyimaging finding
Accessible structured representation
  • Patient —[HAS_CONDITION]→ Type 2 Diabetes
  • Patient —[TAKES_MEDICATION]→ Metformin
  • Metformin —[indicates]→ Type 2 Diabetes
  • Patient —[HAS_RESULT]→ Creatinine 1.6
  • Patient —[HAS_FINDING]→ Cardiomegaly
  • Ibuprofen —[INTERACTION_RISK]→ Metformin
Interactive knowledge graph; click nodes to inspect provenance.

Evidence-backed AI

Intelligence you can audit, not just admire

Every generated claim is verified against retrieved evidence with numeric fidelity checks. Unsupported statements are dropped with uncertainty notes — and claim verdicts are explicit.

Ask a question

Simulated interface mirroring the production contract of POST /v1/reasoning/query. Run it against your own tenant in the playground.

BioMedora Insightreasoning_mode: deterministicConfidenceHigh

Two independent signals support a decline in renal function between 2020 and 2021, with an important caveat about follow-up:

  • SUPPORTED96% confidence12

    Creatinine rose from within normal limits (1.1 mg/dL, 2020-02) to 1.6 mg/dL flagged HIGH on 2021-09-22.

  • SUPPORTED91% confidence2

    The 2021 report explicitly recommended a repeat renal panel in 90 days.

  • PARTIALLY SUPPORTED62% confidence

    Metformin dosing was not re-evaluated in retrieved documents after the creatinine increase.

    Absence of evidence in the current repository — not evidence of absence.

Uncertainty: No documents dated after 2021-12 were found referencing repeat renal testing — flagged as missing follow-up by data-quality analysis.

Evidence

  • [1] DOC-19011 · p.3 · Labs

    Basic metabolic panel: creatinine 1.1 mg/dL (normal).
  • [2] DOC-20455 · p.3 · Labs

    Creatinine 1.6 mg/dL — HIGH. Repeat renal panel in 90 days.

Product tour

See BioMedora in action

Explore a current preview of the BioMedora workspace, or open the running frontend for the complete functional experience.

Live demo

Opens the BioMedora application in a new tab.

app.biomedora.com
acme
E2

Good morning, e2e-admin

Your biomedical intelligence workspace

Document pages processed

18,204

6,796 of 25,000 remaining

AI reasoning requests

847

4,153 credits remaining

Document repository

62 GB

100 GB included

Total logical data

97 GB

Documents + structured + knowledge

Data platform

View details
Document repository62 GB / 100 GB
Structured data11 GB / 25 GB
Knowledge / search24 GB / 50 GB

AI intelligence

Reasoning requests (Local AI included)847 / 5,000
Included

Every AI answer is grounded in retrieved evidence with citations.

Solutions

One intelligence layer, five industries

The same pipeline — privacy, understanding, structure, evidence — powers very different missions. Each workflow maps to real platform capabilities.

  • Healthcare

    • Longitudinal patient intelligence across every chart, note, and feed
    • Chart-prep and referral briefings generated with per-line citations
    • Medication reconciliation with interaction and allergy conflict review
    • Data-quality surveillance: contradictions, stale meds, missed follow-ups
    See it in the playground
  • Pharma

    • Evidence extraction from labels, protocols, and regulatory documents
    • Drug intelligence normalized to RxNorm / ATC with interaction knowledge
    • Safety signal workflows over adverse events linked to source text
    • Literature-grade reasoning with every claim verified against evidence
    See it in the playground
  • Biotech

    • HGVS variant extraction with gene inference from unstructured reports
    • Biomarker and phenotype intelligence via HPO-linked concept graphs
    • Knowledge discovery over provenance-carrying research documents
    • APIs that slot into existing LIMS and analysis pipelines
    See it in the playground
  • Clinical Research

    • De-identified release of clinical documents for secondary research
    • Cohort exploration over structured events instead of chart review
    • Trial screening support with assertion-qualified eligibility facts
    • Reproducible, auditable transformations for regulatory scrutiny
    See it in the playground
  • CRO

    • Automated extraction across sponsor document formats at volume
    • Structured deliverables mapped to your internal data schemas
    • API-driven workflows with idempotency, batches, and signed webhooks
    • Tenant isolation suitable for multi-sponsor operations
    See it in the playground
  • Your workflow here

    If your organization moves biomedical documents, BioMedora can compile them. Tell us about your data and we will map the pipeline to it.

    Talk to BioMedora

API-first

Build biomedical intelligence
into your applications.

Your EHR, LIMS, research platform, data lake, or AI assistant consumes BioMedora through one governed API surface — 141 documented endpoints, typed errors, streaming chat, and signed webhooks.

  1. STEP 1

    Generate credentials

    Create a tenant account and issue a bearer token or scoped API key — secrets shown once, stored hashed.

  2. STEP 2

    Install the SDK

    pip install biomedora-sdk — typed resources for patients, documents, deidentification, reasoning, billing and more.

  3. STEP 3

    Send a document

    POST /v1/documents with an Idempotency-Key; processing stages are observable via the jobs API.

  4. STEP 4

    Receive intelligence

    Entities, assertions, temporal events, timelines, graph neighborhoods — every item traceable to its source sentence.

Python SDK · biomedora_sdk5-minute integration
pip install biomedora-sdk

from biomedora_sdk import Client

client = Client(api_key="YOUR_API_KEY",
                base_url="https://api.biomedora.com")

# 1. Compile a document into structured intelligence
doc = client.documents.create(
    content=open("discharge_summary.txt").read(),
    patient_id="patient_123",
)

# 2. Read the cited longitudinal timeline
timeline = client.patients.timeline(patient_id="patient_123")

# 3. Ask an evidence-grounded question
answer = client.reasoning.query(
    patient_id="patient_123",
    question="What changed after the medication was started?",
)
for claim in answer["claims"]:
    print(claim["status"], claim["confidence"], claim["text"])

Also distributed as biomedora-client — identical API.

cURL
curl -X POST https://api.biomedora.com/v1/nlp/analyze \
  -H "Authorization: Bearer $BIOMEDORA_TOKEN" \
  -H "Content-Type: application/json" \
  -H "X-Request-ID: req-0042" \
  -d '{
    "content": "Started metformin 500 mg BID. No evidence of pneumonia."
  }'
TypeScript — REST
// TypeScript — REST integration (typed fetch)
const res = await fetch("https://api.biomedora.com/v1/reasoning/query", {
  method: "POST",
  headers: {
    Authorization: `Bearer ${process.env.BIOMEDORA_TOKEN}`,
    "Content-Type": "application/json",
    "Idempotency-Key": crypto.randomUUID(),
  },
  body: JSON.stringify({
    patient_id: "patient_123",
    question: "What evidence suggests renal deterioration?",
  }),
});
const answer = await res.json(); // claims[], citations[], uncertainty

Security & privacy

Privacy is part of the pipeline — not an afterthought

BioMedora is designed for privacy-sensitive biomedical workflows: privacy controls are embedded throughout the data lifecycle, from ingestion through AI dispatch.

Full security architecture
  • Fail-closed privacy pipeline

    Detection → pseudonymization → patient-consistent date shifting → independent residual scan. Any high-confidence PHI residue blocks the document outright — empty output, never a warning.

  • Hard tenant isolation

    Server-derived tenant identity on every request; patients namespaced per tenant; cross-tenant access denied and audited — including for administrators.

  • Governed AI routing

    Deterministic NLP first, local models by default. External LLMs require minimized PHI and explicit operator opt-in — and are disabled entirely in BYOC/on-premises deployments.

  • Tamper-evident audit

    Append-only, hash-chained audit records for every sensitive action — who, what, when, outcome, request ID — with verification that pinpoints any tampered entry.

  • Deployment you control

    Single-tenant cloud by default; runs in your AWS account (BYOC) or fully on-premises with in-hospital inference and no external egress.

  • Prompt-injection defense

    Document content is untrusted evidence. Instructions hidden inside clinical text are surfaced transparently and never forwarded to models as directives.

Pricing

Transparent meters, no mystery invoices

Platform subscription plus usage: document pages, reasoning requests, storage GB-months, exports, and optional premium modules. Local AI is included by plan; exactly-once ledgers keep billing reproducible forever.

Explore plans & calculator
  • Developer

    $49/mo · 5k pages incl.

  • Pro

    $499/mo · 25k pages incl.

  • Business

    $2,999/mo · 250k pages incl.

  • Enterprise

    Contract-driven · reserved capacity

FAQ

Frequently asked questions

A biomedical intelligence platform that compiles heterogeneous clinical and research documents into structured evidence, longitudinal patient timelines, knowledge graphs, and searchable intelligence — then runs evidence-grounded AI reasoning on top, all through one API-first surface.

Bring your documents. Leave with intelligence.

Tell us about your document landscape and we will map BioMedora to your workflows — a tailored walkthrough, not a sales script. Or start immediately in the API playground.

No fabricated case studies — judge the product itselfSynthetic demo data onlyYour inquiry details stay with us

We reply from [email protected]. Your details are used only to respond to this inquiry.

Prefer to explore first? Open the playground or read the docs.